I’ll go over the special case of multiple outfit pieces at the end. A character may equip two distinct items both with exactly the same physics for breasts, but consider combining the two items into a single outfit for best results. The same holds for naked body using cloth physics (default if CBBE body built with physics using BodySlide) and putting on a coat or scarf with physics. Avoid equipping both else risk wild physics weirdness. What this means is that if an outfit uses cloth physics for breasts, the character may not also equip cloth physics on a scarf or the coat-tail of an overcoat.
Copying physics from the body to an outfit is simple, but comes with limitations. Physics which optionally comes with CBBE uses cloth physics (applied to the body) to simulate breast movement and jiggle. The method used here will be copying physics from the CBBE reference body to the outfit. I chose this as an example, because the outfit comes with multiple parts. I’m using “ TheKite’s Handmaiden” by Niero and TheKite for an example outfit. Why does an outfit need breast physics? So women dressed in cotton blouses aren’t mistaken for robots, or worse, synths! This guide shows the cloth-physics method to obtain breast physics on a CBBE outfit using Outfit Studio for Fallout 4.